ENGLISH

DNA Damage Detection In Situ, Ex Vivo, and In Vivo: Methods and Protocols

By Deryk T. Loo (auth.) , Vladimir V. Didenko (eds.)

Book information

Publisher
Humana Press
Year
2011
ISBN
1603274081, 9781603274081, 9781603274098
DOI
10.1007/978-1-60327-409-8
ISSN
1064-3745
LCC
QH465.A1 D485 2011
Open Library ID
OL25115471M
Language
english
Format
PDF
Filesize
7 MB (7033797 bytes)
Series
Methods in Molecular Biology 682
Edition
1
Pages
314\328
Topic
Biology Molecular
Orientation
yes
Scanned
no
Time added
2011-08-31 04:54:40
Human Genetics; Gene Function

Description

Recent advances in organic chemistry, fluorescent microscopy, and materials science have created an entirely new range of techniques and probes for imaging DNA damage in molecular and cellular biology. In DNA Damage Detection In Situ, Ex Vivo, and In Vivo: Methods and Protocols, expert researchers explore the latest advances in the area, covering both recent and established techniques to detect and quantify DNA damage at scales ranging from subcellular to the level of a whole live organism. Chapters present all major assays used in molecular and cellular biology for the labeling of DNA damage in situ, ex vivo, and in vivo. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and current, DNA Damage Detection In Situ, Ex Vivo, and In Vivo: Methods and Protocols is an essential handbook for novice and experienced researchers in a variety of fields, including molecular and cellular biology, experimental and clinical pathology, toxicology, radiobiology, oncology, embryology, experimental pharmacology, drug design, and environmental science.

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