ENGLISH

Galactose Regulon of Yeast: From Genetics to Systems Biology

By Paike Jayadeva Bhat

Book information

Year
2008
ISBN
3540740147, 9783540740148, 9783540740155
Open Library ID
OL16864889M
Language
english
Format
PDF
Filesize
5 MB (5207853 bytes)
Edition
1
Pages
220\229
Topic
Biology Biophysics
Scanned
yes
Time added
2011-06-04 13:46:07

Description

The galactose regulon of yeast is one of the best studied regulons. It is an ideal paradigm for demonstrating fundamental and evolving concepts in biology and is used in this book as a model system to explain various facets of conventional and modern biology. The book starts with a brief historical overview on yeast research, i.e. early observations in enzyme adaptation, classical genetics, formulating hypotheses based on genetic inference. This is followed by molecular genetics of the galactose regulon, isolation of genes and testing of the hypotheses. The power of mutational analysis in deciphering molecular mechanisms is conveyed. Further, contemporary topics such as genomics, evolution, single cell analysis of transcriptional switching, binary and graded responses, biological consequences of feed back regulation in genetic circuits, and stochasticity are addressed.

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