ENGLISH

Heat Shock

By J. T. Lis (auth.) , Ph. D. Bruno Maresca , Ph. D. Susan Lindquist (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
1991
ISBN
978-3-642-76681-7, 978-3-642-76679-4
DOI
10.1007/978-3-642-76679-4
Language
english
Format
PDF
Filesize
31 MB (32571172 bytes)
Edition
1
Pages
320\307
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Cell Biology; Biochemistrygeneral; Pharmacology/Toxicology; Immunology; Canc

Description

During the last years the heat shock response has been stu- died as a model system to analyze control mechanisms regula- ting the synthesis of heat shock proteins providing impor- tant general insight into the regulation of gene expression. But the major revelation, which has sparked interest from all quarters of biology, is the discovery that heat shock proteins play major roles in an extraordinary variety of normal cellular processes. They are the focus of investiga- tions in many areas of cell biology, including protein traf- ficking, signal transduction, DNS replication, transcrip- tion, protein synthesis, and in the assembly of di- verse protein structures. These aspects are thoroughly trea- ted in the book, as are the implications in immunology, in- fec- tious diseases, chronic degeneration, hyperthermia, and can- cer research.

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