Mathematical and Computational Oncology: First International Symposium, ISMCO 2019, Lake Tahoe, NV, USA, October 14–16, 2019, Proceedings

Description

This book constitutes the refereed proceedings of the First International Symposium on Mathematical and Computational Oncology, ISMCO'2019, held in Lake Tahoe, NV, USA, in October 2019. The 7 full papers presented were carefully reviewed and selected from 30 submissions. The papers are organized in topical sections named: Tumor evolvability and intra-tumor heterogeneity; Imaging and scientific visualization for cancer research; Statistical methods and data mining for cancer research (SMDM); Spatio-temporal tumor modeling and simulation (STTMS). Front Matter ....Pages i-xxiii Front Matter ....Pages 1-1 Phylogenies Derived from Matched Transcriptome Reveal the Evolution of Cell Populations and Temporal Order of Perturbed Pathways in Breast Cancer Brain Metastases (Yifeng Tao, Haoyun Lei, Adrian V. Lee, Jian Ma, Russell Schwartz)....Pages 3-28 Modeling the Evolution of Ploidy in a Resource Restricted Environment (Gregory Kimmel, Jill Barnholtz-Sloan, Hanlee Ji, Philipp Altrock, Noemi Andor)....Pages 29-34 Front Matter ....Pages 35-35 cmIF: A Python Library for Scalable Multiplex Imaging Pipelines (Jennifer Eng, Elmar Bucher, Elliot Gray, Lydia Grace Campbell, Guillaume Thibault, Laura Heiser et al.)....Pages 37-43 Front Matter ....Pages 45-45 Accurate and Flexible Bayesian Mutation Call from Multi-regional Tumor Samples (Takuya Moriyama, Seiya Imoto, Satoru Miyano, Rui Yamaguchi)....Pages 47-61 Flexible Data Trimming for Different Machine Learning Methods in Omics-Based Personalized Oncology (Victor Tkachev, Anton Buzdin, Nicolas Borisov)....Pages 62-71 Front Matter ....Pages 73-73 Towards Model-Based Characterization of Biomechanical Tumor Growth Phenotypes (Daniel Abler, Philippe Büchler, Russell C. Rockne)....Pages 75-86 Population Modeling of Tumor Growth Curves, the Reduced Gompertz Model and Prediction of the Age of a Tumor (Cristina Vaghi, Anne Rodallec, Raphaelle Fanciullino, Joseph Ciccolini, Jonathan Mochel, Michalis Mastri et al.)....Pages 87-97 Back Matter ....Pages 99-99