ENGLISH

Diagnostic Cytogenetics

By Friedel Wenzel (auth.) , Prof. Dr. Rolf-Dieter Wegner Ph.D. (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
1999
ISBN
978-3-642-47813-0, 978-3-642-59918-7
DOI
10.1007/978-3-642-59918-7
Language
english
Format
PDF
Filesize
9 MB (9381118 bytes)
Series
Springer Lab Manual
Edition
1
Pages
460\464
Time added
2014-01-18 08:00:00
Human Genetics; Cell Biology; Molecular Medicine

Description

In addition to the traditional cytogenetics still used as the basic methodology for everyday clinical diagnosis, new molecular cytogenetic techniques provide a useful basis for routine diagnosis. Flourescence in situ hybridization (FISH) has become a standard technique, and comparative genomic hybridization (CGH), sprectral karyotyping (SKY), and multi-color FISH have shown their potential for diagnostic purposes. Following a section on tissue culture, chromosome staining and basic information about karyotyping, nomenclature and quality standards, protocols of relevance for comprehensive cytogenetic diagnostics are presented.

Similar books