ENGLISH

Ten Years of Progress in GW/P Body Research

By Edward K. L. Chan , Marvin J. Fritzler (auth.) , Marvin J. Fritzler (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2013
ISBN
978-1-4614-5106-8, 978-1-4614-5107-5
DOI
10.1007/978-1-4614-5107-5
Language
english
Format
PDF
Filesize
4 MB (4281849 bytes)
Series
Advances in Experimental Medicine and Biology 768
Edition
1
Pages
276\279
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
generalHuman Genetics; Cell Biology; Biochemistry

Description

GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chan’s group in 2002. These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA degradation. The detailed biological functions of these cytoplasmic structures are still being uncovered and the idea for this book is to provide the history of the discovery and the major work from different laboratories that has led to the characterization and elucidation of the structure and function of these new multiple subcellular structures.

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