ENGLISH

Purines in Cellular Signaling: Targets for New Drugs

By PhD (eds.) , J. W. Daly (auth.) , Kenneth A. Jacobson PhD , John W. Daly PhD , Vincent Manganiello MD

Book information

Publisher
Springer-Verlag New York
Year
1990
ISBN
978-1-4612-7996-9, 978-1-4612-3400-5
DOI
10.1007/978-1-4612-3400-5
Language
english
Format
PDF
Filesize
19 MB (19424405 bytes)
Edition
1
Pages
448\458
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
general; Pharmacology/Toxicologygeneral; Pharmacy; BiochemistryMedicine/Public Health

Description

Research on purine derivatives as potent and selective modulators of physiologic functions has moved to center stage. This volume covers the biology and chemistry of purines and of their receptors broadly under these section headings: - Adenosine Receptors and Effector Systems - Adenine Nucleotide Receptors and Effector Systems - Phosphodiesterase Enzymes and Inhibitors The presentations focus on the potential development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Xanthines (caffeine and theophylline) represent one class of such agents. This volume is for pharmacologists, biochemists, and medical chemists in research labs of universities, gov- ernment, and the pharmaceutical industry.

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