Cerebral Ischemic Reperfusion Injuries (CIRI)

Description

This volume is focused on subjects related to cerebral ischemia and reperfusion injuries after acute stroke. All chapters are selected from the Sixth Elite Stroke meeting named Pangu Stroke Conference and written by members of world leading laboratories of stroke studies. The contents cover both clinical and bench studies, from basic components of cerebral arterial system to clinical reperfusion injury cases, from reperfusion caused programmed cell death and astrocyte activation to oxidative stress and nitric oxide after reperfusion, from extracellular matrix and inflammation to a role of diabetes after reperfusion, from small artery disorders to collateral circulation and blood pressure control after reperfusion. Wei-Jian Jiang, Chairman of New Era Stroke Care and Research Institute of PLA Rocket Force General Hospital, Beijing, China. Wengui Yu, Professor and Director of Comprehensive Stroke & Cerebrovascular Center, University of California, Irvine Yan Qu, Professor and Director of Neurosurgery at the Second Affiliated Hospital of Air Force Medical University, Xi’an, China. Zhongsong Shi, Professor of Neurosurgery at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. Ben-yan Luo, Professor and Chair of Neurology at the First Affiliated Hospital of Zhejiang University. John H. Zhang, Professor of Anesthesiology and Physiology at Loma Linda University School of Medicine, Loma Linda, CA, USA. Front Matter ....Pages i-xvii Gelatinase-Mediated Impairment of Microvascular Beds in Cerebral Ischemia and Reperfusion Injury (Shanyan Chen, Hailong Song, Jiankun Cui, Joel I. Shenker, Yujie Chen, Grace Y. Sun et al.)....Pages 1-14 Characters of Ischemic Stroke and Recanalization Arteries (Qingqing Dai, Shujuan Li, Junfa Li)....Pages 15-34 Cerebral Ischemic Reperfusion Injury (CIRI) Cases (Weijian Jiang, Yi-Qun Zhang)....Pages 35-41 CIRI After Early Recanalization (Qingmeng Chen, Min Lou)....Pages 43-56 Programmed Cell Death in CIRI (Ruili Wei, Yang Xu, Jie Zhang, Benyan Luo)....Pages 57-82 Reactive Astrocytes in Cerebral Ischemic Reperfusion Injury (Abhishek Mishra, Rachana Nayak, Dandan Sun)....Pages 83-100 Oxidative Stress and Nitric Oxide in Cerebral Ischemic Reperfusion Injury (Junning Ma, Zhong Liu, Zhongsong Shi)....Pages 101-119 Extracellular Matrix in Stroke (Yao Yao)....Pages 121-144 Inflammation and Ischemic Stroke (Junwei Hao, Kai Zheng, Heng Zhao)....Pages 145-161 Cerebral Vascular Injury in Diabetic Ischemia and Reperfusion (Wenlu Li, Haibin Dai)....Pages 163-169 Ischemia/Reperfusion Damage in Diabetic Stroke (Poornima Venkat, Michael Chopp, Jieli Chen)....Pages 171-192 Current Understanding of Pathology and Therapeutic Status for CADASIL (Suning Ping, Li-Ru Zhao)....Pages 193-203 Blood Pressure and Cerebral Ischemic Reperfusion Injury (Weijian Jiang, Chen Li, Mohamad Orabi, Wuwei Feng)....Pages 205-213 Collateral Circulation and Cerebral Reperfusion After Ischemic Stroke (Qinghai Huang, Wanling Wen, Myles McCrary, Ling Wei)....Pages 215-230 Controlled Reperfusion Against Ischemia Reperfusion Injury (Weijian Jiang, Jin Lv, Ying-Ying Zhang, Kai Wang)....Pages 231-243 Therapeutic Window Beyond Cerebral Ischemic Reperfusion Injury (Wengui Yu, Liping Liu)....Pages 245-259