ENGLISH

Microarrays for an Integrative Genomics

By Isaac S. Kohane , Alvin Kho , Atul J. Butte

Book information

Publisher
The MIT Press
Year
2002
ISBN
026211271X, 9780262112710
Open Library ID
OL16040056M
Language
english
Format
DJVU
Filesize
3 MB (3026268 bytes)
Series
Computational Molecular Biology
Edition
1
Pages
325\325
Topic
Medicine
Library
Kolxo3
DPI
300
Time added
2011-01-23 12:00:00

Description

Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.

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