ENGLISH

RNA and DNA Editing: Methods and Protocols

By H. Ulrich Göringer , Holger Stark , Cordula Böhm , Bjoern Sander , Monika M. Golas (auth.) , Ruslan Aphasizhev (eds.)

Book information

Publisher
Humana Press
Year
2011
ISBN
1617790176, 9781617790171
DOI
10.1007/978-1-61779-018-8
ISSN
1064-3745
Language
english
Format
PDF
Filesize
6 MB (5917391 bytes)
Series
Methods in Molecular Biology 718
Edition
1
Pages
275\290
Topic
Biology Molecular
Orientation
yes
Scanned
no
Time added
2011-08-31 04:54:40
Human Genetics; Enzymology

Description

The recent expansion in diversity of RNA and DNA editing types has stimulated the development of many unique genetic, molecular, biochemical, and computational approaches to biological issues. In RNA and DNA Editing: Methods and Protocols, leading experts in the field introduce methods developed over the last few years to study editing substrates, mechanisms of specificity, and functions of RNA and DNA editing enzymes and complexes. Sections of the book are dedicated to state-of-the art techniques which enable investigation of uracil insertion/deletion RNA editing in mitochondrion of Trypanosoma brucei, adenosine to inosine RNA editing, cytidine to uracil RNA and DNA editing, as well as tRNA editing and RNA modifications. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNA and DNA Editing: Methods and Protocols seeks to inspire the further development of these vital and powerful techniques.

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