ENGLISH

Assessing Bioavailablility of Drug Delivery Systems: Mathematical Modeling

Book information

Publisher
CRC Press
Year
2005
ISBN
9780849330445, 0849330440
Open Library ID
OL22626130M
Language
english
Format
PDF
Filesize
8 MB (7994076 bytes)
Edition
1
Pages
227\227
Library
mexmat
Time added
2009-11-09 02:42:13

Description

Writing for pharmacology researchers and practitioners in medicine or pharmacology, Vergnaud (materials and chemical engineering, U. de Saint-Etienne, France) and Rosca (polymer Chemistry and technology, Polytechnic U., Bucharest, Romania) explain mathematical modeling to correlate in-vitro and in-vivo controlled-release drug dosage forms. They present methods for calculating the profiles of plasma levels obtained with controlled-release dosage forms, and provide examples and case studies to illustrate the techniques. The master curves they present use dimensionless numbers in repeated doses, either for the time or for the plasma drug concentration, and so can be applied to any drug with a linear pharmacokinetics.

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