Heterocyclic Antitumor Antibiotics

Description

From the reviews: "Heterocyclic antitumor antibiotics represent a broad class of natural products that are of widespread interest … . Thus, a well-written, up-to-date account of progress in the study of such compounds is expected to be well received. … this monograph certainly has sufficient scientific value to merit inclusion in most academic libraries and in industrial laboratories concerned with antibacterial and anticancer agent discovery. Individual researchers, on the other hand, might first wish to weigh the extent to which this far-ranging collection of reviews deals sufficiently with topics of specific interest to their research groups before acquiring a personal copy." (Gary I. Dmitrienko, Journal of the American Chemical Society, Vol. 129, 2007) Synthesis of Biologically Active Heterocyclic Stilbene and Chalcone Analogs of Combretastatin....Pages 1-51 Pyrrole Natural Products with Antitumor Properties....Pages 53-92 Synthesis of Carbolines Possessing Antitumor Activity....Pages 93-128 Diazo and Diazonium DNA Cleavage Agents: Studies on Model Systems and Natural Product Mechanisms of Action....Pages 129-152 Novel Synthetic Antibacterial Agents....Pages 153-206 Overcoming Bacterial Resistance: Role of β-Lactamase Inhibitors....Pages 207-246