ENGLISH

Thermodynamic theory of site-specific binding processes in biological macromolecules

By Enrico Di Cera

Book information

Publisher
CUP
Year
1995
ISBN
9780521416597, 0521416590
LCC
QP517.B42 D5 1995
Open Library ID
OL783257M
Language
english
Format
DJVU
Filesize
2 MB (2578327 bytes)
Pages
312\312
Library
Kolxo3
DPI
300
Time added
2010-07-29 05:14:56

Description

This book provides a systematic treatment of the thermodynamic theory of site-specific effects in biological macromolecules. It describes the phenomenological and conceptual bases required to allow a mechanistic understanding of these effects from analysis of experimental data. The thermodynamic theory also results in novel experimental strategies that enable the derivation of information on local, site-specific properties of a macromolecular system from analysis of perturbed global properties. The treatment focuses on binding phenomena, but is amenable to extension to the analysis of other cooperative processes, such as folding and helixSHcoil transitions. It covers a subject that bridges the gap between thermodynamics and the experimental analysis of the molecular basis of cooperativity in biological macromolecules and will be of interest to biochemists and biophysicists.

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