Carbohydrate Drug Design

Description

Content: Overview. Carbohydrates and drug design: what is new in this book / Anatole A. Klyosov -- Carbohydrate therapeutics: new developments and strategies / Zbigniew J. Witczak -- Cancer. Development of a polysaccharide as a vehicle to improve the efficacy of chemotherapeutics / David Platt, Anatole A. Klyosov, and Eliezer Zomer -- DAVANAT and colon cancer: preclinical and clinical (phase I) studies / Anatole A. Klyosov, Eliezer Zomer, and David Platt -- Synthesis and biological activity of doxo-galactose and doxo-galactomannan, new conjugates of doxorubicin with D-galactose and 1,4, [beta]-D-galactomannan / Anatole A. Klyosov ... [et al.] -- Human immunodeficiency virus. Carbohydrate-based vaccines against HIV/Aids / Lai-Xi Wang -- Toward a carbohydrate-based HIV-1 vaccine / Daniel Calarese ... [et al.] -- Pathogen management. Cationic polysaccharides in the treatment of pathogenic Candida infections / Avital Mazar Ben-Josef, David Platt, and Eliezer Zomer -- New approaches in synthesis and computational studies. Synthetic methods to incorporate [alpha]-linked 2-amino-2-deoxy-D-glucopyranoside and 2-amino-2-deoxy-D-galactopyranoside residues into glycoconjugate structures / Robert J. Kerns and Peng Wei -- Systematic synthesis of aminosugars and their stereoselective glycosylation / Jinhua Wang and Cheng-Wei Tom Chang -- Practical applications of computational studies of the glycosylation reaction / Dennis M. Whitfield and Tomoo Nukada.