ENGLISH

Melatonin : therapeutic value and neuroprotection

By Venkatramanujan Srinivasan , Gabriella Gobbi , Samuel D. Shillcutt , Sibel Suzen.

Book information

Publisher
CRC Press/Taylor and Francis
Year
2015
ISBN
9781482220100, 1482220105
Language
english
Format
PDF
Filesize
8 MB (8119868 bytes)
Pages
xxvi, 564\564
Time added
2014-09-24 15:19:23

Description

There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin's neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases and other ailments. Topics include:The basic aspects of melatonin's physiology, including its production, bioavailability, and metabolism.  Read more... Front Cover; Contents; Preface; Acknowledgments; Editors; Contributors; Chapter 1: Melatonin Production and Bioavailability; Chapter 2: Deviations of Melatonin Levels and Signaling in Aging and Diseases : Options and Limits of Treatment; Chapter 3: Pineal Gland Volume and Melatonin; Chapter 4: Melatonin's Beneficial Effects in Metabolic Syndrome with Therapeutic Applications; Chapter 5: Therapeutic Applications of Melatonin in Pediatrics; Chapter 6: Neuroprotective Effect of Melatonin on Perinatal Hypoxia-Ischemia; Chapter 7: Melatonin as a Therapeutic Agent for Sepsis; Chapter 8: Melatonin's Cardioprotective RoleChapter 9: Melatonin : Therapeutic Value and Neuroprotection in Stroke; Chapter 10: Melatonin's Antiapoptotic Activity in Neurodegenerative Diseases; Chapter 11: MT2 Melatonin Receptors : Their Role in Sleep and Neuropsychiatric Disorders; Chapter 12: Melatonin : Its Hepatoprotective Actions and the Role of Melatonin Receptors; Chapter 13: Melatonin Signaling in the Control of Plasmodium Development and Replication; Chapter 14: Melatonin : Regulator of Adult Hippocampal Neurogenesis; Chapter 15: Comparison of Neuroprotective Effect of Melatonin in the Nigrostriatal and Mesolimbic Dopaminergic Systems of the Zitter RatChapter 16: Melatonin's Neuroprotective Role in Parkinson's Disease; Chapter 17: Neuroprotective Role of Melatonin in Glaucoma; Chapter 18: Melatonin Receptors and Their Preventive Role in Carcinogenesis; Chapter 19: Enhancement of Antitumor Activity of Ursolic Acid by Melatonin in Colon Cancer Cells; Chapter 20: Synthetic Melatonin Receptor Ligands; Chapter 21: Evaluation of Synthetic Melatonin Analog Antioxidant Compounds; Chapter 22: Melatonin's Analogues in GlaucomaChapter 23: Melatonergic Drugs as Therapeutic Agents for Insomnia and Depressive Disorders; Chapter 24: Agomelatine : A Neuroprotective Agent with Clinical Utility beyond Depression and Anxiety; Chapter 25: Melatonergic Antidepressant Agomelatine in Depressive and Anxiety Disorders; Chapter 26: Effects of Melatonin and Melatonergic Drugs in Transgenic Mouse Models of Alzheimer's Disease; Chapter 27: Melatonin's Mitochondrial Protective Role in Alzheimer's Mice : Role of Melatonin Receptors; Chapter 28: Melatonin and Its Therapeutic Implications in Injuries of the Developing Brain and RetinaChapter 29: Melatonin's Protection against Human Prion-Mediated Neurotoxicity; Chapter 30: Melatonin's Protection against Methamphetamine Toxicity in Neuroblastoma Cells; Chapter 31: Melatonin's Beneficial Effects on Dopaminergic Neurons in the Rat Model of Parkinson's Disease; Chapter 32: Antiepileptic Effects of Melatonin; Chapter 33: Analgesic Effects of Melatonin; Chapter 34: Effects of Melatonin on the Proliferative and Differentiative Activity of Neural Stem Cells; Chapter 35: Role of Melatonin in Collagen Synthesis.

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