Chemotherapy in Neonates and Infants

Description

This book provides a comprehensive overview of pediatric oncology, discussing drug therapy and treatment in children under the age of 1 year. It is the first volume to focus on chemotherapy in newborns and infants, especially the daily clinical practice and treatment protocols. Intended as a practical manual, it addresses all the major topics related to pediatric oncology in an accessible and easy-to-use format. It examines topics in pediatric oncology therapeutics, including drug metabolism, excretion, toxicity, drugs that can be used for each week or month of the patient’s life, dose adjustment and treatment protocols.Chemotherapy in Neonates and Infants focuses on the safe treatment of children in the first year of life, and is aimed at pediatric oncology/hematology institutions, clinics and departments. It is particularly valuable for researchers, pediatric oncology physicians, pediatric and neonatology physicians, oncology pharmacists and the other healthcare professionals directly involved in the chemotherapy of neonates and infants. Front Matter ....Pages i-xix Introduction (Carolina Witchmichen Penteado Schmidt)....Pages 1-15 Protocols Used in Chemotherapy Treatment of Neonates and Infants (Carolina Witchmichen Penteado Schmidt)....Pages 17-76 Pharmacokinetics and Pharmacodynamics of Chemotherapy Drugs in Neonates and Infants (Carolina Witchmichen Penteado Schmidt)....Pages 77-106 Peculiarities of Most Commonly Used Chemotherapy Drugs in Neonates and Infants (Carolina Witchmichen Penteado Schmidt)....Pages 107-114 Adjuvant Drugs Used in Chemotherapy for Neonates and Infants (Carolina Witchmichen Penteado Schmidt)....Pages 115-124 Drug Interactions in Neonates and Infants (Carolina Witchmichen Penteado Schmidt)....Pages 125-136 Toxicity (Carolina Witchmichen Penteado Schmidt)....Pages 137-146 Tumor Lysis in Neonates and Infants (Carolina Witchmichen Penteado Schmidt)....Pages 147-149 Chemotherapy in Neonates and Infants with Cancer and Other Congenital Diseases: Down Syndrome and HIV (Carolina Witchmichen Penteado Schmidt)....Pages 151-155 Stem Cell Transplantation in Neonates and Infants (Carolina Witchmichen Penteado Schmidt)....Pages 157-166 Back Matter ....Pages 167-198