ENGLISH

Hox Modules in Evolution and Development

By David E. K. Ferrier

Book information

Publisher
CRC Press
Year
2023
ISBN
2022033628, 2022033629, 9780367522582, 9780367522605, 9781003057215
Language
english
Format
PDF
Filesize
25 MB (26650640 bytes)
Series
Evolutionary Cell Biology
Pages
218\219
Time added
2023-03-18 12:29:03

Description

Few, if any, genes have had the same level of impact on the field of evolutionary-developmental biology (evo-devo) as the Hox genes. These genes are renowned for their roles in patterning the body plans and development of the animal kingdom. This is complemented by the distinctive organisation of these genes in the genome, with them frequently being found as clusters in which gene position is linked to when and where the individual genes are expressed, particularly during embryogenesis. This book provides the latest overviews of Hox gene organisation and function for major clades of animals from across the animal kingdom. With the rapidly increasing availability of high-quality whole genome sequences from an ever-expanding range of species, it is becoming increasingly evident that there is great diversity in the organisation of Hox genes. These great strides in genome sequencing are wedded to important developments in our ability to detect expression and disrupt gene function in species that are not traditionally genetically-amenable animals. These technical developments are integrated with wide taxon-sampling in this volume to provide new perspectives on the roles of Hox genes in understanding fundamental issues such as embryo patterning, mechanisms of gene regulation, homology, evolvability, evolutionary novelties, phylogeny, the role of gene and genome duplications in evolution, and ancestral states for major clades of animals. Key features Integrative overviews from major animal groups including, arthropods, vertebrates, echinoderms, mollusks and other spiralians. Perspectives gleaned from the latest genome sequence and gene expression data. Individual chapters written by world-leading experts in Hox genes and evo-devo in each animal group. Cover Half Title Series Page Title Page Copyright Page Dedication Contents Series Preface Preface About the Editor Contributors Chapter 1: Introduction to Hox Modules in Evolution and Development Chapter 2: Multiple Layers of Complexity in the Regulation of the Bithorax Complex of Drosophila Chapter 3: The Role of Hox Genes in the Origins and Diversification of Beetle Horns Chapter 4: Duplication and Evolution of Hox Clusters in Chelicerata (Arthropoda) Chapter 5: Structural Constraints in Hox Clusters: Lessons from Sharks and Rays Chapter 6: Evolution of Cyclostome Hox Clusters Chapter 7: Hox Genes in Echinoderms Chapter 8: Hox Genes in Mollusca Chapter 9: The Evolution of Hox Genes in Spiralia Index

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