ENGLISH

Microbial Protein Toxins

By Ryan Ratts , John R. Murphy (auth.) , Manfred J. Schmitt , Raffael Schaffrath (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2005
ISBN
9783540235620, 3-540-23562-0
DOI
10.1007/b94860
ISSN
1610-2096
LCC
QP632.M52 M53 2005
Open Library ID
OL3316626M
Language
english
Format
PDF
Filesize
7 MB (6842463 bytes)
Series
Topics in Current Genetics 11
Edition
1
Pages
237\243
Library
Kingdwarf
Time added
2010-01-07 06:59:20
general; Cell BiologyMicrobiology; Medical Microbiology; Biochemistry

Description

Since the initial establishment of Robert Koch’s postulates in the nineteenth century, microbial protein toxins have been recognized as a major factor of bacterial and fungal virulence. An increasing number of proteins produced and secreted by various bacteria, yeasts and plants are extremely toxic and most of them developed remarkably "intelligent" strategies to enter, to penetrate and to finally kill a eukaryotic target cell by modifying or blocking essential cellular components. This book describes the strategies employed by protein toxins to render their pro- and eukaryotic producers a selective growth advantage over competitors. In providing an up-to-date overview on the mode of protein toxin actions, it accommodates biomedically and biologically relevant toxin model systems. As a result, it significantly broadens our perspective on biochemical architecture and molecular ploy behind the lethal principles of pro- and eukaryotic toxins.

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