ENGLISH

Alkaptonuria and Ochronosis

By Jozef Rovenský; Tibor Urbánek; Boldišová Oľga; James A. Gallagher

Book information

Publisher
Springer
Year
2015
ISBN
9783319151083, 3319151088
Language
english
Format
EPUB
Filesize
3 MB (3061846 bytes)
Pages
156\0
Time added
2020-05-30 10:08:03

Description

This book comprehensively describes alkaptonuria and ochronosis. Beginning with the history, genetics, pathophysiology and diagnostics of the disease, the authors subsequently present a detailed characterization of its clinical manifestation in the spine, peripheral joints, eyes, ears, visceral organs and respiratory tract, its pathological anatomy and histology, as well as differential diagnosis. This is complemented by the latest data on therapy and experimental models of alkaptonuria, and supported by several case reports. Numerous pictures and radiological images document the clinical symptoms, giving the reader a solid understanding of the disease. On the basis of the editor’s and authors’ own extensive observations, the book offers an analysis of protein metabolism and aromatic amino acids in the context of alkaptonuria. Written by international experts in the field, the book offers a valuable reference guide for healthcare professionals working in rheumatology, dermatology, pulmonology, otolaryngology and histopathology.

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