ENGLISH

Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity

By Gary A. Silverman , David A. Lomas

Book information

Year
2007
ISBN
9812569634, 9789812569639, 9789812707543
Open Library ID
OL13169534M
Language
english
Format
PDF
Filesize
6 MB (6012940 bytes)
Edition
1
Pages
672\670
Time added
2011-06-04 13:46:07

Description

Massive thrombosis or bleeding, hereditary angioedema, Alzheimer's disease, diabetic angiopathy and tumor invasion are some of the human diseases associated with serpins. In addition, mutations that alter serpin conformations (the serpinopathies) lead to lung disease, cirrhosis and a form of familial dementia. The goal of this text is to present the current knowledge on the molecular and cellular basis of serpins and their diseases.

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