ENGLISH

Structural Approaches to Sequence Evolution: Molecules, Networks, Populations

By Peter F. Stadler (auth.) , Peter Schuster , Dr. Ugo Bastolla , Professor Dr. Markus Porto , Dr. H. Eduardo Roman , Dr. Michele Vendruscolo (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2007
ISBN
978-3-540-35305-8, 978-3-540-35306-5
DOI
10.1007/978-3-540-35306-5
Language
english
Format
PDF
Filesize
8 MB (8520703 bytes)
Series
Biological and Medical Physics, Biomedical Engineering
Edition
1
Pages
367\374
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Biophysics and Biological Physics;Bioinformatics

Description

Structural requirements constrain the evolution of biological entities at all levels, from macromolecules to their networks, right up to populations of biological organisms. Classical models of molecular evolution, however, are focused at the level of the symbols - the biological sequence - rather than that of their resulting structure. Now recent advances in understanding the thermodynamics of macromolecules, the topological properties of gene networks, the organization and mutation capabilities of genomes, and the structure of populations make it possible to incorporate these key elements into a broader and deeply interdisciplinary view of molecular evolution. This book gives an account of such a new approach, through clear tutorial contributions by leading scientists specializing in the different fields involved.

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