ENGLISH

Exosomes in cardiovascular diseases : biomarkers, pathological and therapeutic effects

By Junjie , Cretoiu , Sanda; Xiao

Book information

Publisher
Springer
Year
2017
ISBN
978-981-10-4397-0, 9811043973, 978-981-10-4396-3
Language
english
Format
PDF
Filesize
7 MB (7057084 bytes)
Series
Advances in experimental medicine and biology 998
Pages
307\300
Time added
2017-10-15 16:00:00
Cardiovascular system -- Diseases -- Molecular asp

Description

The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist"--Publisher's description. Read more... Abstract: The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Read more... Front Matter ....Pages i-vii Front Matter ....Pages 1-1 The Multifaceted Functions of Exosomes in Health and Disease: An Overview (Claudia Arenaccio, Maurizio Federico)....Pages 3-19 Front Matter ....Pages 21-21 Exosomes: Nanocarriers of Biological Messages (Alice Conigliaro, Simona Fontana, Stefania Raimondo, Riccardo Alessandro)....Pages 23-43 Functional Role of Cardiovascular Exosomes in Myocardial Injury and Atherosclerosis (Maarten Vanhaverbeke, Diane Gal, Paul Holvoet)....Pages 45-58 Front Matter ....Pages 59-59 Exosomes as Diagnostic Biomarkers in Cardiovascular Diseases (Felix Jansen, Qian Li)....Pages 61-70 Exosomes-Based Biomarkers for the Prognosis of Cardiovascular Diseases (Yihua Bei, Pujiao Yu, Dragos Cretoiu, Sanda Maria Cretoiu, Junjie Xiao)....Pages 71-88 Front Matter ....Pages 89-89 Exosomes as New Intercellular Mediators in Development and Therapeutics of Cardiomyocyte Hypertrophy (Qi Huang, Benzhi Cai)....Pages 91-100 Dual Behavior of Exosomes in Septic Cardiomyopathy (Valter Vinícius Silva Monteiro, Jordano Ferreira Reis, Rafaelli de Souza Gomes, Kely Campos Navegantes, Marta Chagas Monteiro)....Pages 101-112 Pathological Effects of Exosomes in Mediating Diabetic Cardiomyopathy (Esam S. B. Salem, Guo-Chang Fan)....Pages 113-138 Peripartum Cardiomyopathy: Do Exosomes Play a Role? (Huanyu Gu, Qiying Dai, Zhuyuan Liu, Hongbao Wang, Jianhua Yao, Lei Zhou)....Pages 139-149 Vascular Calcification Regulation by Exosomes in the Vascular Wall (Marcel Liberman, Luciana Cavalheiro Marti)....Pages 151-160 Front Matter ....Pages 161-161 Cardioprotective Effects of Exosomes and Their Potential Therapeutic Use (Shengguang Ding, Jingying Zhang, Qiying Dai, Mengfei Zhao, Haitao Huang, Yiming Xu et al.)....Pages 163-177 Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease (Etsu Suzuki, Daishi Fujita, Masao Takahashi, Shigeyoshi Oba, Hiroaki Nishimatsu)....Pages 179-185 Exosomes Derived from Embryonic Stem Cells as Potential Treatment for Cardiovascular Diseases (Yao-Hua Song, Lianbo Shao, Yu Zhang, Jin Zhou, Bin Liu, Xiangbin Pan et al.)....Pages 187-206 Cardiac Progenitor-Cell Derived Exosomes as Cell-Free Therapeutic for Cardiac Repair (E. A. Mol, M. J. Goumans, J. P. G. Sluijter)....Pages 207-219 Therapeutic Potential of Hematopoietic Stem Cell-Derived Exosomes in Cardiovascular Disease (Jana Radosinska, Monika Bartekova)....Pages 221-235 Cardiac Telocyte-Derived Exosomes and Their Possible Implications in Cardiovascular Pathophysiology (Mirca Marini, Lidia Ibba-Manneschi, Mirko Manetti)....Pages 237-254 Circulating Exosomes in Cardiovascular Diseases (Yihua Bei, Ting Chen, Daniel Dumitru Banciu, Dragos Cretoiu, Junjie Xiao)....Pages 255-269 Therapeutic Effects of Ischemic-Preconditioned Exosomes in Cardiovascular Diseases (Shengguang Ding, Zhiqing Fan, Che Lin, Qiying Dai, Jinzhe Zhou, Haitao Huang et al.)....Pages 271-281 Front Matter ....Pages 283-283 Exosomes: Outlook for Future Cell-Free Cardiovascular Disease Therapy (Bahar Barani, Sheeja Rajasingh, Johnson Rajasingh)....Pages 285-307

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