ENGLISH

Placenta and Trophoblast Volume 2 Methods And Protocols (Methods in Molecular Medicine)

By Michael J. Soares , Joan S. Hunt

Book information

Year
2006
ISBN
9781588296085, 9781592599899, 1588296083
Open Library ID
OL9670099M
Language
english
Format
PDF
Filesize
4 MB (4388066 bytes)
Edition
1
Pages
452\476
Time added
2011-06-04 13:46:07

Description

A collection of cutting-edge laboratory techniques for the study of the trophoblast and placental biology. The techniques presented range from experimental animal models, to animal and human placental organ and cell culture systems, to morphological, biochemical, and molecular strategies for assessing trophoblast/placental growth, differentiation and function. Volume 2 provides readily reproducible protocols for studying trophoblast invasion, maternal immune cell responses to pregnancy, and the hormone producing capabilities of the placenta. There are also methods to investigate the barrier function of the placenta, its role in regulating the transport of nutrients and wastes, and the adaptations of trophoblast cells and the placenta to disease. Highlights include techniques to analyze trophoblast cell interactions with the uterine vasculature and immune cells, and the endocrine functions of the placenta. A companion first volume concentrates on methods for investigate embryo-uterine implantation, trophoblast cell development, and the organization and molecular characterization of the placenta.

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