ENGLISH

T Cell Subsets: Cellular Selection, Commitment and Identity

By Harvey Cantor , Laurie Glimcher , and Frederick W. Alt (Eds.)

Book information

Publisher
Elsevier, Academic Press
Year
2004
ISBN
978-0-12-022483-8
ISSN
0065-2776
Open Library ID
OL24221367M
Language
english
Format
PDF
Filesize
4 MB (4259397 bytes)
Series
Advances in Immunology 83
Edition
1
Pages
1-304\331
Topic
Medicine immunology
Scanned
yes
Time added
2011-06-04 13:46:07
Медицинские дисциплины;Иммунология и аллергология;

Description

This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers

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