ENGLISH

Telomerase Inhibition: Strategies and Protocols

By Trygve O. Tollefsbol (auth.) , Trygve O. Tollefsbol (eds.) , Lucy G. Andrews

Book information

Publisher
Humana Press
Year
2007
ISBN
9781588296832, 1588296830
DOI
10.1007/978-1-60327-070-0
LCC
QP606.T44 A537 2007
Open Library ID
OL23155193M
Language
english
Format
PDF
Filesize
8 MB (8499069 bytes)
Series
Methods in Molecular Biology 405
Edition
1
Pages
193\190
Topic
Biology
Library
kolxoz-dop
Time added
2010-02-18 13:16:04
Cell Biology; Cancer Research; Human Genetics; Biogeneral

Description

Due in part to the selective nature of telomerase inhibition as an anticancer approach, the field has expanded considerably in the past decade. The recent advances in methods of telomerase inhibition encompass many different areas of research including molecular biology, cell biology, biochemistry, oncology and gerontology. Telomerase Inhibition provides methods and protocols for those researchers. The techniques described in this book should provide the researcher with a diverse and comprehensive set of tools with which to study telomerase inhibition. Leaders in the field provide recently developed methods that have widespread application such as targeting the telomerase holoenzyme, its RNA template and other elements associated with telomerase activity. Additional methods involving the screening of telomerase inhibitors and telomerase inhibition combined with other chemotherapeutic agents are presented. This text, on the cutting edge of the field, will provide investigators with the most recent methods applied to the expanding field of telomerase inhibition.

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