Articular Cartilage Dynamics

Description

This book explains the anatomy and physiology of cartilage tissue in an integrated way. The emphasis is on how cartilage tissue functions and maintains homeostasis in a challenging mechanical environment. Supported by hundreds of references, the book posts new hypotheses explaining how cartilage adapts and achieves homeostasis in vivo, and tests them against available data. This exploratory approach creates a sense of discovery that the reader can join, or perhaps test themselves through their own research. The main benefit will be obtained by research students and professors looking to understand the deeper concepts that will further their own research, or clinicians (including health professionals and surgeons) who want to gain a deeper physiological understanding of cartilage tissue, which can then serve as a basis for more rational clinical decision-making they need to make on a daily basis. To help bridge the gap between basic science and clinically relevant joint disease, applications and interpretations of key physiological concepts are discussed in the context of osteoarthritis at the end of most chapters. Front Matter ....Pages i-lxiii Introduction to Articular Cartilage (David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky)....Pages 1-63 Cartilage Tissue Homeostasis (David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky)....Pages 65-243 Cartilage Tissue Dynamics (David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky)....Pages 245-309 Lubrication, Friction, and Wear in Diarthrodial Joints (David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky)....Pages 311-359 A Systems Approach to Articular Cartilage (David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky)....Pages 361-428 Osmotic Pressure, Solid Stress, and the Diffuse Double Layer (David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky)....Pages 429-467 Theory for Modeling Articular Cartilage (David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky)....Pages 469-560 Back Matter ....Pages 561-738