ENGLISH

Leukocyte Adhesion Molecules

By Alan S. Rosenthal (auth.) , Timothy A. Springer Ph.D. , Donald C. Anderson M.D. , Robert Rothlein Ph.D. , Alan S. Rosenthal (eds.)

Book information

Publisher
Springer-Verlag New York
Year
1990
ISBN
978-1-4612-7927-3, 978-1-4612-3234-6
DOI
10.1007/978-1-4612-3234-6
Language
english
Format
PDF
Filesize
9 MB (9442573 bytes)
Edition
1
Pages
287\293
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
general; Oncology; Anthropology; ImmunologyLife Sciences

Description

Leukocyte adhesion molecules promise to be highly effective as antigens in the antibody-directed leucocyte elimination treatment prior to grafting or in cases of acute and chronic inflammatory disease. This comprehensive review of contemporary research provides thorough discussions of the structure of these molecules, their in vitro function, and the role that they play in vivo as evidenced by results shown in inflammatory models where antibodies against these molecules are given to inhibit their function. The blend of basic science and clinical applications provides clear evidence of the biological relevance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion.

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