Liver Cancers: From Mechanisms to Management
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This book explores in detail the primary liver cancers of hepatocellular carcinoma and cholangiocarcinoma examining the pathogenesis of disease along with diagnosis and current management options together with exploration of future treatment strategies and areas of controversy. Furthermore, the book highlights management of the common secondary malignancies and touches on benign liver tumours and how to best manage these. Written in a clear and didactic style, this volume includes summaries of the key learning points and questions so that the reader can gauge their knowledge and understanding. This book is aimed to broaden the knowledge base of primary care physicians, general physicians along with specialists in hepatology, oncology and hepato-biliary surgery Front Matter ....Pages i-xvi Front Matter ....Pages 1-1 The Epidemiology of Hepatocellular Carcinoma (Philip Johnson)....Pages 3-11 Surveillance for Hepatocellular Carcinoma (Eleanor J. Taylor, Ian A. Rowe)....Pages 13-21 Roles of the Immune System in the Development and Progression of Hepatocellular Carcinoma (João Maurício, Helen Reeves, Caroline L. Wilson)....Pages 23-37 Mechanisms of Disease: The Damaged Genome in HCC (Matthew Hoare)....Pages 39-58 The Role of Histology in Hepatocellular and Cholangiocarcinoma (Alberto Quaglia)....Pages 59-65 Diagnosis and Staging of Hepatocellular Carcinoma (HCC) (Vinay Kumar Balachandrakumar, Nadya Fatima Jabbar, David White, Nicholas Stern)....Pages 67-82 The Role of Liver Resection for the Treatment of Hepatocellular Carcinoma (Mikael H. Sodergren, Dinesh Sharma)....Pages 83-97 Liver Transplantation for the Treatment of Hepatocellular Carcinoma (Aileen Marshall)....Pages 99-108 The Role of Interventional Radiology and Image-Guided Ablation in Primary Liver Cancer (Jen-Jou Wong, Nabil Kibriya)....Pages 109-122 Transarterial Embolization Therapies in Hepatocellular Carcinoma: Principles of Management (Tim Cross, Jonathan C. Evans)....Pages 123-138 Radioembolisation in Hepatocellular Carcinoma: Principles of Management (Bruno Sangro, Andrea Casadei Gardini)....Pages 139-152 Oncotherapies for HCC (Alexa Childs, Tim Meyer)....Pages 153-165 Front Matter ....Pages 167-167 Mixed Hepatocellular/Cholangiocarcinomas: Current Perspectives and Management (Ray Tan, Alberto Quaglia, Paul J. Ross)....Pages 169-178 Epidemiology and Pathogenesis of Cholangiocarcinoma (Stephen McClements, Shahid A. Khan)....Pages 179-186 Diagnosis and Staging of Cholangiocarcinoma (Jessica R. Hale, Olusola O. Faluyi)....Pages 187-198 Cholangiocarcinoma: From Mechanisms to Management (Leonard M. Quinn, Nicholas Bird, Robert Jones, David Vass, Hassan Malik)....Pages 199-212 Oncotherapies for Cholangiocarcinoma (Oliver Pickles, Yuk Ting Ma)....Pages 213-223 Front Matter ....Pages 225-225 Novel Treatments for Advanced Cholangiocarcinoma (Jenny Cotton, Angela Lamarca, Mairéad G. McNamara, Juan W. Valle)....Pages 227-243 Making the Diagnosis of Neuroendocrine Tumour Disease (Vandana M. Sagar, Mona Elshafie, Tahir Shah)....Pages 245-258 Treatment of Neuroendocrine Tumour Disease (Andrew R. Moore, Vincent S. Yip)....Pages 259-273 Front Matter ....Pages 275-275 Colorectal Liver Metastasis (Rafael Diaz-Nieto, Graeme J. Poston)....Pages 277-293 Benign Liver Tumours (James Pape, Charles Imber)....Pages 295-307 Back Matter ....Pages 309-312
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