ENGLISH

Deep brain stimulation: indications and applications

By Bieber , Allan J.; Duffy , Penelope S.; Lee , Kendall H

Book information

Publisher
Pan Stanford Publishing
Year
2017
ISBN
978-981-4669-89-4, 978-981-4669-90-0, 197-198-198-2, 981466989X, 9781315364759, 1315364751
Language
english
Format
PDF
Filesize
12 MB (12969806 bytes)
Pages
486\474
Time added
2017-01-21 08:00:00
Brain stimulation.;Brain stimulation;Therapeutic u

Description

Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation–evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.

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