Neuroendocrine Tumors

Description

New research has shown that neuroendocrine tumors are more common than previously thought. Progress in our understanding of the molecular pathogenesis of these not-so-rare cancers has resulted in renewed interest in developing innovative therapeutic options. In particular, novel molecular targeted agents have been shown to have significant anti-tumor activity, and integration of these therapies has led to critical advances in management. In this volume, an outstanding group of the world’s leaders in the field have assembled to convey their knowledge of the epidemiology, biology, and management of all the major types of neuroendocrine tumors. The book takes a multi-modality approach to understanding disease processes and therapeutics, including chapters on medical and surgical treatment as well as a chapter devoted to imaging. Throughout, the authors emphasize recent advances in our understanding of molecular biology and the subsequent emerging therapeutic options. Front Matter....Pages i-xi Global Epidemiology of Neuroendocrine Tumors....Pages 1-10 Pathology....Pages 11-27 Multiple Endocrine Neoplasia....Pages 29-49 Other Genetic Syndromes (TSC, VHL, NF1, etc.)....Pages 51-60 Imaging of Neuroendocrine Tumors....Pages 61-78 Surgical Management of Sporadic Gastrointestinal Neuroendocrine Tumors....Pages 79-99 Management of Neuroendocrine Tumor Hormonal Syndromes....Pages 101-115 Management of Metastatic Carcinoid Tumors....Pages 117-136 Medical Management of Islet Cell Carcinoma....Pages 137-155 Poorly Differentiated Neuroendocrine Tumors....Pages 157-176 Hereditary and Sporadic Medullary Thyroid Carcinoma....Pages 177-193 Adrenocortical Carcinoma....Pages 195-220 Pheochromocytoma....Pages 221-244 Merkel Cell Carcinoma....Pages 245-258 Back Matter....Pages 259-267