ENGLISH

Biology of C Reactive Protein in Health and Disease

By Waliza Ansar , Shyamasree Ghosh (auth.)

Book information

Publisher
Springer India
Year
2016
ISBN
978-81-322-2678-9, 978-81-322-2680-2
DOI
10.1007/978-81-322-2680-2
Language
english
Format
PDF
Filesize
9 MB (9423118 bytes)
Edition
1
Pages
XXX, 301\324
Time added
2016-07-20 04:00:00
Human Physiology; Molecular Medicine; Biotechnolog

Description

This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail. The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP.

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