ENGLISH

Maturation Phenomenon in Cerebral Ischemia IV: Apoptosis and/or Necrosis, Neuronal Recovery vs. Death, and Protection Against Infarction

By Umeo Ito , Toshihiko Kuroiwa , Nicolás G. Bazán , Victor L. Marcheselli , Igor Klatzo (auth.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2001
ISBN
978-3-540-41107-9, 978-3-642-59446-5
DOI
10.1007/978-3-642-59446-5
Language
english
Format
PDF
Filesize
16 MB (16931218 bytes)
Edition
1
Pages
284\279
Time added
2013-12-12 02:00:00
Neurology; Neurosurgery; Emergency Medicine; Anest

Description

The maturation phenomenon, first described by Ito et al. in 1975, refers to postischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CA1 pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evident that ischemic damage is not a sudden event, but a process potentially susceptible to therapeutic intervention. Since then a growing number of studies have improved our knowledge on mechanisms of cell death and recovery. This volume contains the presentations of the 4th international symposium, held in New Orleans in October/November 1999, grouped in sections covering apoptosis and/or necrosis, neuronal recovery vs. death, and protection against infarction. It outlines the present status of investigations and provides further stimulation for research in this field.

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