ENGLISH

RHO Family GTPases

By Ed Manser (auth.) , Ed. Manser (eds.)

Book information

Publisher
Springer Netherlands
Year
2005
ISBN
978-1-4020-3461-9, 978-1-4020-3462-6
DOI
10.1007/1-4020-3462-8
Language
english
Format
PDF
Filesize
6 MB (6702176 bytes)
Series
Proteins and Cell Regulation 3
Edition
1
Pages
298\306
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Cell Biology; Proteomics; Biochemistrygeneral; Cancer Research; Molecular Medicine

Description

Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted. The book includes an overview of how Rho GTPases become activated which is complemented by an extensive Chapter by Darerca Owen and Helen Mott who unravel the beautiful molecular details given to us by the many structural studies of Rho GTPases. The key areas currently being investigated in relation to these ubiquitous proteins are described for both in vitro and in vivo systems. These are presented in a format that ensures the reader can approach the topic with minimal background knowledge, while ultimately bringing the subject to the level of an expert. Timely and highly authoritative, this volume illuminates newer findings, particularly as they relate to Rho proteins in vertebrate biology.

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