Introduction to biomolecular structure and biophysics : basics of biophysics

Description

This comprehensive book presents a modern concept in biophysics based on recently published research. It highlights various aspects of the biophysical fundamentals and techniques that are currently used to study different physical properties of biomolecules, and relates the biological phenomenon with the underlying physical concepts. The content is divided into nine chapters summarizing the structural details of proteins, including recently discovered novel folds, higher order structures of nucleic acids, as well as lipids and the physical forces governing the macromolecular interactions which are essential for the various biological processes. It also provides insights into the recent advances in biophysical techniques including Hydrogen Deuterium Exchange with Mass Spectrometry (HDX-MS), Small angle X-ray scattering (SAXS) and Cryo Electron Microscopy (cryo EM), supplemented with interesting experimental data. It is a valuable reference resource for anyone with a desire to gain a better understanding of the fundamentals of biophysical concepts and techniques of important biomolecules. Front Matter ....Pages i-xvii Principles of Protein Structure and Function (Juliana Helena Costa Smetana, Gauri Misra)....Pages 1-32 Protein Folding (Smriti Shrivastava)....Pages 33-56 Nucleic Acid Structure and Function (Jyotika Rajawat)....Pages 57-83 Higher-Order Nucleic Acid Structures (Preeti Arivaradarajan)....Pages 85-113 Macromolecular Interactions (Shipra Gupta, Arunima Verma)....Pages 115-137 Lipid and Membrane Structures (Charul Sharma, Priya Vrat Arya, Sohini Singh)....Pages 139-182 Membrane Biophysics (Sushant Singh, Naresh C. Bal)....Pages 183-204 Techniques in Biophysics (Vijay Kumar Srivastava)....Pages 205-243 Advance Techniques in Biophysics (Mariana Fioramonte, Fabio Cezar Gozzo, Cristiano Luis Pinto de Oliveira, Rodrigo V. Portugal, Marin van Heel)....Pages 245-274