ENGLISH

Poxvirus Vascular Endothelial Growth Factor (VEGF) Homologs of Orf Virus

By McFadden G. , Moyer R.

Book information

DOI
10.1006/rwcy.2000.03015
Language
english
Format
PDF
Filesize
170 kB (174497 bytes)
Pages
4\4
Topic
Mathematics Algebra
Library
mexmat
Time added
2009-07-20 03:45:11

Description

To date, a viral homolog of vascular endothelial growth factor (VEGF) has been discovered in only one poxvirus, namely orf virus of sheep. Orf virus encodes two such proteins, each of which possesses characteristic cysteine spacing motifs found in cellular VEGF family members. Viral VEGF binds to the members of the same family of cell surface receptors as its cellular counterparts and has proangiogenic activity.

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