ENGLISH

Mitochondria and the Heart

By José Marín-García (eds.)

Book information

Publisher
Springer US
Year
2005
ISBN
0-387-22824-1-254, 0-387-23187-0, 0-387-23632-5, 0-387-25574-5, 9780387255743
DOI
10.1007/b135603
LCC
RC670.5.M33 A85 2005
Open Library ID
OL3309965M
Language
english
Format
PDF
Filesize
25 MB (25800106 bytes)
Series
Developments in Cardiovascular Medicine 256
Edition
1
Pages
400\411
Topic
Medicine
Library
Kingdwarf
Time added
2010-01-07 06:59:20
Cardiology

Description

The function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases. José Marín-García is affiliated with The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey and the Department of Physiology & Biophysics, UMDNJ – Robert Wood Johnson Medical School, Piscataway, New Jersey.

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