Textbook of Pathology

Description

The seventh edition of the renowned Textbook of Pathology, by Harsh Mohan, has been fully revised to provide the most up to date information on the latest developments in the field. Divided into three sections - General Pathology, Haematology and Lymphoreticular Tissues, and Systemic Pathology - the new edition covers numerous diseases, their causes, mechanisms, pathophysiology, classification, morphology, and clinical aspects. Each topic concludes with a summary of key points and features illustrative images, diagrams and tables. Most chapters include a clinical case related to the topic, presenting its history and findings, finishing with important questions which are answered in the Appendix section. The textbook is accompanied by a revised free booklet `Pathology Quick Review and MCQs' (9789351523703), to help pathology trainees prepare for examinations. Key points Fully revised, new edition of renowned Textbook of Pathology Presents clinical cases and questions and answers for each topic Includes free booklet `Pathology Quick Review and MCQs' (9789351523703) Previous edition published in 2010 Cover......Page 1 Copyright......Page 4 Foreword......Page 7 Preface......Page 9 Contents......Page 11 STUDY OF PATHOLOGY......Page 17 EVOLUTION OF PATHOLOGY......Page 18 SUBDIVISIONS OF PATHOLOGY......Page 23 CELL INJURY......Page 25 MORPHOLOGY OF REVERSIBLE CELL INJURY......Page 33 INTRACELLULAR ACCUMULATIONS......Page 35 PIGMENTS......Page 38 MORPHOLOGY OF IRREVERSIBLECELL INJURY (CELL DEATH)......Page 42 ADAPTIVE DISORDERS......Page 53 AGEING......Page 58 THE IMMUNE SYSTEM......Page 60 DISEASES OF IMMUNITY......Page 66 AMYLOIDOSIS......Page 82 CLINICAL CASE 1......Page 93 HOMEOSTASIS......Page 94 DISTURBANCES OF BODY WATER......Page 96 DISTURBANCES OF ELECTROLYTES AND pH OF BLOOD......Page 104 HAEMODYNAMIC DERANGEMENTS......Page 105 CLINICAL CASE 2......Page 131 ACUTE INFLAMMATION......Page 132 CHRONIC INFLAMMATION......Page 150 HEALING......Page 171 CLINICAL CASE 3......Page 180 INTRODUCTION......Page 181 SPIROCHAETES AND MYCOBACTERIA......Page 183 DISEASES CAUSED BY FUNGI......Page 189 DISEASES CAUSED BY VIRUSES......Page 190 DISEASES CAUSED BY PARASITES......Page 194 TORCH COMPLEX......Page 198 NOMENCLATURE AND CLASSIFICATION......Page 200 CHARACTERISTICS OF TUMOURS......Page 202 EPIDEMIOLOGY AND MOLECULAR PATHOGENESIS OF CANCER......Page 213 CARCINOGENS AND CARCINOGENESIS......Page 225 CLINICAL ASPECTS OF NEOPLASIA......Page 238 ENVIRONMENTAL DISEASES......Page 247 NUTRITIONAL DISEASES......Page 254 GENETIC DISEASES......Page 267 OTHER PAEDIATRIC DISEASES......Page 274 BONE MARROW AND HAEMATOPOIESIS......Page 277 ERYTHROPOIESIS......Page 280 ANAEMIA—GENERAL CONSIDERATIONS......Page 284 HYPOCHROMIC ANAEMIAS......Page 288 MEGALOBLASTIC ANAEMIAS......Page 296 HAEMOLYTIC ANAEMIAS AND ANAEMIA DUE TO BLOOD LOSS......Page 302 BONE MARROW DISORDERS......Page 317 CLINICAL CASE 4......Page 319 CLINICAL CASE 5......Page 320 DISORDERS OF PLATELETS......Page 321 BLEEDING DISORDERS (HAEMORRHAGIC DIATHESIS)......Page 325 BLOOD GROUPS AND BLOOD TRANSFUSION......Page 333 CLINICAL CASE 6......Page 336 LYMPH NODES: NORMAL AND REACTIVE......Page 337 WHITE BLOOD CELLS: NORMAL AND REACTIVE......Page 340 Lymphohaematopoietic Malignancies (LEUKAEMIAS-LYMPHOMAS): GENERAL......Page 349 MYELOID NEOPLASMS......Page 351 LYMPHOID NEOPLASMS: GENERAL......Page 360 HODGKIN’S DISEASE......Page 364 NON-HODGKIN’S LYMPHOMAS-LEUKAEMIAS......Page 368 PLASMA CELL DISORDERS......Page 376 LANGERHANS CELL HISTIOCYTOSIS......Page 381 SPLEEN......Page 382 THYMUS......Page 384 CLINICAL CASE 8......Page 385 NORMAL STRUCTURE......Page 386 ARTERIOSCLEROSIS......Page 387 VASCULITIS......Page 397 ANEURYSMS......Page 402 COMMON DISEASES OF VEINS......Page 405 DISEASES OF LYMPHATICS......Page 406 TUMOURS AND TUMOUR-LIKE LESIONS......Page 407 CLINICAL CASE 9......Page 412 NORMAL STRUCTURE AND CLASSIFICATION......Page 413 HEART FAILURE......Page 415 CONGENITAL HEART DISEASE......Page 418 ISCHAEMIC HEART DISEASE......Page 423 HYPERTENSIVE HEART DISEASE......Page 433 RHEUMATIC HEART DISEASE......Page 434 NON-RHEUMATIC ENDOCARDITIS......Page 440 VALVULAR DISEASES AND DEFORMITIES......Page 445 MYOCARDIAL DISEASES......Page 448 PERICARDIAL DISEASES......Page 453 TUMOURS OF THE HEART......Page 455 INTERVENTIONS......Page 456 CLINICAL CASE 10......Page 457 NORMAL STRUCTURE OF LUNGS......Page 458 PAEDIATRIC LUNG DISEASE......Page 459 PULMONARY VASCULAR DISEASE......Page 462 PULMONARY INFECTIONS......Page 464 CHRONIC OBSTRUCTIVE PULMONARY DISEASE......Page 474 CHRONIC RESTRICTIVE PULMONARY DISEASE......Page 483 TUMOURS OF LUNGS......Page 493 DISEASES OF PLEURA......Page 501 CLINICAL CASE 12......Page 503 EYE......Page 504 EAR......Page 511 NOSE AND PARANASAL SINUSES......Page 512 LARYNX......Page 516 CLINICAL CASE 13......Page 519 ORAL SOFT TISSUES......Page 520 TEETH AND PERIODONTAL TISSUES......Page 525 SALIVARY GLANDS......Page 531 CLINICAL CASE 14......Page 536 OESOPHAGUS......Page 537 STOMACH......Page 542 SMALL INTESTINE......Page 560 APPENDIX......Page 577 LARGE BOWEL......Page 579 PERITONEUM......Page 590 CLINICAL CASE 16......Page 592 LIVER......Page 593 BILIARY TRACT......Page 639 EXOCRINE PANCREAS......Page 646 CLINICAL CASE 18......Page 650 CLINICAL CASE 19......Page 651 KIDNEY......Page 652 LOWER URINARY TRACT......Page 701 CLINICAL CASE 21......Page 706 TESTIS AND EPIDIDYMIS......Page 707 PENIS......Page 718 PROSTATE......Page 719 CLINICAL CASE 22......Page 725 VULVA......Page 726 VAGINA......Page 728 CERVIX......Page 729 MYOMETRIUM AND ENDOMETRIUM......Page 735 FALLOPIAN TUBES......Page 744 OVARIES......Page 745 PLACENTA......Page 757 SECTION III......Page 760 Chapter 23: The Breast......Page 761 NON-NEOPLASTIC CONDITIONS......Page 762 BREAST TUMOURS......Page 764 CLINICAL CASE 24......Page 774 Chapter 24: The Skin......Page 775 DERMATOSES......Page 776 TUMOURS AND TUMOUR-LIKE LESIONS......Page 786 CLINICAL CASE 25......Page 797 BASIC CONCEPT OF ENDOCRINES......Page 798 PITUITARY GLAND......Page 800 ADRENAL GLAND......Page 803 THYROID GLAND......Page 808 PARATHYROID GLANDS......Page 822 ENDOCRINE PANCREAS......Page 824 MISCELLANEOUS ENDOCRINE TUMOURS......Page 835 CLINICAL CASE 27......Page 836 SKELETAL SYSTEM......Page 837 JOINTS......Page 857 SKELETAL MUSCLES......Page 864 CLINICAL CASE 28......Page 866 GENERAL FEATURES......Page 867 SOFT TISSUE TUMOURS......Page 869 CLINICAL CASE 29......Page 878 CENTRAL NERVOUS SYSTEM......Page 879 PERIPHERAL NERVOUS SYSTEM......Page 900 CLINICAL CASE 30......Page 903 INTRODUCTION......Page 904 EXFOLIATIVE CYTOLOGY......Page 905 INTERVENTIONAL CYTOLOGY......Page 915 CLINICAL CASE 2 (Chapter 4, Page 115)......Page 922 CLINICAL CASE 5 (Chapter 10, Page 304)......Page 923 CLINICAL CASE 9 (Chapter 13, Page 396)......Page 924 CLINICAL CASE 12 (Chapter 15, Page 487)......Page 925 CLINICAL CASE 17 (Chapter 19, Page 634)......Page 926 CLINICAL CASE 20 (Chapter 20, Page 690)......Page 927 CLINICAL CASE 23 (Chapter 22, Page 744)......Page 928 CLINICAL CASE 27 (Chapter 25, Page 820)......Page 929 CLINICAL CASE 30 (Chapter 28, Page 887)......Page 930 NORMAL ORGANS......Page 931 CLINICAL SIGNIFICANCE......Page 932 SECTION I: GENERAL PATHOLOGY......Page 939 SECTION III: SYSTEMIC PATHOLOGY......Page 941 APPENDICES......Page 944 A......Page 946 B......Page 948 C......Page 949 D......Page 952 E......Page 953 F......Page 954 G......Page 955 H......Page 956 I......Page 958 L......Page 959 M......Page 960 O......Page 962 P......Page 963 S......Page 965 T......Page 967 V......Page 968 Z......Page 969