Medicinal Mushrooms: Recent Progress in Research and Development

Description

Presents the latest R & D information on medicinal mushrooms from diverse geographical locations Offers comprehensive coverage of the most important application areas of medicinal mushrooms Includes contributions by eminently experienced researchers in the field of medicinal mushrooms Medicinal mushrooms are increasingly gaining attention worldwide because of their pharmacologically bioactive compounds, which have demonstrated potent and unique clinical properties. Scientific studies carried out during the last decade have confirmed their efficacy in treating a wide range of diseases. Extracts and bioactive compounds obtained from mushrooms have been used medicinally as anticancer, immunomodulator, antibacterial, antiviral, anti-inflammatory, anti-atherosclerotic, neuroprotectant, cardioprotectant, antioxidant, and anti-hypoglycemic agents, and in stem cell-based therapies. Introducing readers to the latest developments in, and ongoing research efforts on, medicinal mushrooms, this book gathers articles contributed by eminent researchers in different disciplines and from around the globe. Highlighting the tremendous potential of mushrooms for the development of new drugs, the topics covered include but are not limited to: Recent progress in research on the pharmaceutical potential of medicinal mushrooms and prospects for their clinicalapplication Edible mushroom neuronutraceuticals: Basis of therapeutics Overview of therapeutic efficacy of mushrooms Mushrooms – a wealth of resources for prospective stem cell-based therapies Mushrooms as potential natural cytostatics Front Matter ....Pages i-xix Recent Progress in Research on the Pharmacological Potential of Mushrooms and Prospects for Their Clinical Application (Susanna M. Badalyan, Anush Barkhudaryan, Sylvie Rapior)....Pages 1-70 Edible Mushrooms as Neuro-nutraceuticals: Basis of Therapeutics (V. R. Remya, Goutam Chandra, K. P. Mohanakumar)....Pages 71-101 Overview of Therapeutic Efficacy of Mushrooms (Sindhu Ramesh, Mohammed Majrashi, Mohammed Almaghrabi, Manoj Govindarajulu, Eddie Fahoury, Maali Fadan et al.)....Pages 103-141 Mushrooms as Potential Natural Cytostatics (Mirjana Stajić, Jelena Vukojević, Jasmina Ćilerdžić)....Pages 143-168 Immunomodulatory Aspects of Medicinal Mushrooms (Seema Patel)....Pages 169-185 Mushrooms: A Wealth of Resource for Prospective Stem Cell-Based Therapies (Marthandam Asokan Shibu, Tamilselvi Shanmugam, Dinesh Chandra Agrawal, Chih-Yang Huang)....Pages 187-205 Aqueous and Ethanolic Extracts of Medicinal Mushroom Trametes versicolor Interact with DNA: A Novel Genoactive Effect Contributing to Its Antiproliferative Activity in Cancer Cells (Tze-Chen Hsieh, Hsiao Hsiang Chao, Yang Chu, Barbara B. Doonan, Joseph M. Wu)....Pages 207-221 Role of Mushrooms in Neurodegenerative Diseases (Wooseok Lee, Ayaka Fujihashi, Manoj Govindarajulu, Sindhu Ramesh, Jack Deruiter, Mohammed Majrashi et al.)....Pages 223-249 Medicinal Mushrooms as Novel Sources for New Antiparasitic Drug Development (Daniel A. Abugri, Joseph A. Ayariga, Boniface J. Tiimob, Clement G. Yedjou, Frank Mrema, William H. Witola)....Pages 251-273 Antiviral Potency of Mushroom Constituents (Prabin Pradeep, Vidya Manju, Mohammad Feraz Ahsan)....Pages 275-297 Discovery of Muscarine Leading to the Basic Understanding of Cholinergic Neurotransmission and Various Clinical Interventions (Sindhu Ramesh, Mohammed Majrashi, Mohammed Almaghrabi, Manoj Govindarajulu, Maali Fadan, Jack Deruiter et al.)....Pages 299-316 Current Research on Medicinal Mushrooms in Italy (Giuseppe Venturella, Paola Saporita, Maria Letizia Gargano)....Pages 317-333 African Medicinal Mushrooms: Source of Biopharmaceuticals for the Treatment of Noncommunicable Diseases – A Review (Kenneth Anchang Yongabi)....Pages 335-347 Tiger Milk Mushroom (The Lignosus Trinity) in Malaysia: A Medicinal Treasure Trove (Shin-Yee Fung, Chon-Seng Tan)....Pages 349-369 Diversity and Medicinal Value of Mushrooms from the Himalayan Region, India (Sanjana Kaul, Malvi Choudhary, Suruchi Gupta, Dinesh Chandra Agrawal, Manoj K. Dhar)....Pages 371-389 L-Ergothioneine: A Potential Bioactive Compound from Edible Mushrooms (Saraswathy Nachimuthu, Ruckmani Kandasamy, Ramalingam Ponnusamy, Jack Deruiter, Muralikrishnan Dhanasekaran, Sivasudha Thilagar)....Pages 391-407 Mycotherapy of Antrodia salmonea: A Taiwanese Medicinal Mushroom (Palaniyandi Karuppaiya, Abdul Khader Akbar)....Pages 409-419