Networking of Mutagens in Environmental Toxicology

Description

This book covers the latest environmental issues based on current research objectives. All chapters are fundamentally interlinked and focus on deciphering the networking of mutagens in environmental toxicity and human health. Our changing environment, climate, and lifestyle factors are growing concerns in the 21st century. The existing mutagens, either physical or chemical, are responsible for environmental toxicity. These toxicants are carcinogenic and not limited to naturally occurring chemicals or biologicals, but can also be man-made, such as 'radiation'. The networking of mutagens can have a broad range of effects on both the environment and human health. Accordingly, the respective chapters explore the networking of mutagens in connection with environmental toxicity, and address: 1. Extant types of man-made radiation and their effects on the environment and biological systems2. Heavy metal contaminations: Effects on environmental health3. Networking of environmental pollutants in the air, dust, soil, water, and natural toxins in the environment: Exposure and health4. The molecular interaction of environmental carcinogens with DNA: An oncoinformatics approach5. Fundamentals of nonotoxicity, carcinogenicity, mutagenic and neurotoxicity in environmental health6. The role of antioxidants and medicinal plants in reducing the impacts of disease-causing pollutants A sequel to Perspectives in Environmental Toxicology, this book highlights the latest developments in the field of environmental toxicology. It offers a valuable resource for researchers, scholars and graduate students alike. Front Matter ....Pages i-xii Role of Radiation in DNA Damage and Radiation Induced Cancer (Vaishali Chandel, Gaurav Seth, Priyank Shukla, Dhruv Kumar)....Pages 1-23 Mechanistic Effect of Heavy Metals in Neurological Disorder and Brain Cancer (Sandeep Kumar Agnihotri, Kavindra Kumar Kesari)....Pages 25-47 Molecular Mechanisms of Heavy Metal Toxicity in Cancer Progression (Pragati Singh, Deepak Tiwari, Manish Mishra, Dhruv Kumar)....Pages 49-79 Burden of Occupational and Environmental Hazards of Cancer (Meenu Gupta, Anupam Dhasmana)....Pages 81-97 Environmental Toxicants and Male Reproductive Toxicity: Oxidation-Reduction Potential as a New Marker of Oxidative Stress in Infertile Men (Shubhadeep Roychoudhury, Manas Ranjan Saha, Mriganka Mouli Saha)....Pages 99-115 System Network Biology Approaches in Exploring of Mechanism Behind Mutagenesis ( Anukriti, Swati Uniyal, Anupam Dhasmana, Meenu Gupta, Kavindra Kumar Kesari, Qazi Mohd. Sajid Jamal et al.)....Pages 117-136 Ecotoxicological Effects of Heavy Metal Pollution on Economically Important Terrestrial Insects (Oksana Skaldina, Jouni Sorvari)....Pages 137-144 Contamination Links Between Terrestrial and Aquatic Ecosystems: The Neonicotinoid Case (Victor Carrasco-Navarro, Oksana Skaldina)....Pages 145-157 RAGE Exacerbate Amyloid Beta (Aβ) Induced Alzheimer Pathology: A Systemic Overview (Firoz Akhter, Asma Akhter, Kavindra Kumar Kesari, Ruheena Javed, Janne Ruokolainen, Tapani Vuorinen)....Pages 159-170 Elucidation of Scavenging Properties of Nanoparticles in the Prevention of Carcinogenicity Induced by Cigarette Smoke Carcinogens: An In Silico Study (Qazi Mohammad Sajid Jamal, Ali H. Alharbi, Mohtashim Lohani, Mughees Uddin Siddiqui, Varish Ahmad, Anupam Dhasmana et al.)....Pages 171-183