Above the Gene, Beyond Biology: Toward a Philosophy of Epigenetics
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Epigenetics is currently one of the fastest-growing fields in the sciences. Epigenetic information not only controls DNA expression but links genetic factors with the environmental experiences that influence the traits and characteristics of an individual. What we eat, where we work, and how we live affects not only the activity of our genes but that of our offspring as well. This discovery has imposed a revolutionary theoretical shift on modern biology, especially on evolutionary theory. It has helped to uncover the developmental processes leading to cancer, obesity, schizophrenia, alcoholism, and aging, and to facilitate associated medial applications such as stem cell therapy and cloning. Above the Gene, Beyond Biology explores how biologists in this booming field investigate and explain living systems. Jan Baedke offers the first comprehensive philosophical discussion of epigenetic concepts, explanations, and methodologies so that we can better understand this “epigenetic turn” in the life sciences from a philosophical perspective. CONTENTS......Page 10 ACKNOWLEDGMENTS ......Page 12 INTRODUCTION. WHAT IS EPIGENETICS?......Page 16 1. HOW EPIGENETICS DEALS WITH BIOLOGICAL COMPLEXITY......Page 28 2. CHALLENGES OF EPIGENETICS IN LIGHT OF THE EXTENDED EVOLUTIONARY SYNTHESIS......Page 56 3. CAUSAL EXPLANATION......Page 105 4. MECHANISTIC EXPLANATION......Page 144 5. ASSESSING THE EXPLANATORY POWER OF EPIGENETICS......Page 183 CONCLUSION. A PHILOSOPHY OF EPIGENETICS......Page 216 NOTES ......Page 232 REFERENCES ......Page 260 INDEX ......Page 316
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