ENGLISH

Molecular Basis of Hematopoiesis

By Patricia Ernst (auth.) , Amittha Wickrema , Barbara Kee (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2009
ISBN
9780387858159, 0387858156, 0387858164, 9780387858166
DOI
10.1007/978-0-387-85816-6
LCC
QP92 .M64 2009
Open Library ID
OL23533203M
Language
english
Format
PDF
Filesize
4 MB (3700433 bytes)
Edition
1
Pages
257\260
Topic
Medicine
Library
avaxhome.ws
Time added
2010-05-31 15:29:46
Cancer Research; Cell Biology; Pharmacology/Toxico

Description

Although much is known with respect to blood cell formation and function many new concepts in regulation of hematopoietic stem cell commitment and subsequent survival, proliferation and differentiation of progenitors have been elucidated in the last five years. Our understanding of the microenvironment where stem cells reside (the niche) and commit to distinct blood types has grown significantly in recent years. Furthermore, blood cells have been used as the key model system to study microRNA function and the role of micro RNAs in transformation of normal cells into cancer cells. The current volume "Molecular Basis of Hematopoiesis," edited by Amittha Wickrema & Barbara Kee provides the most recent developments in the above mentioned areas in addition to a chapter on utilization of basic science knowledge for treatment of blood diseases. Each chapter in this book has been written and edited by faculty in major academic and research institutions around the world working directly in hematopoietic cell research who are pushing the frontiers of biology.

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