ENGLISH

Epigenetics and Dermatology

By Christopher C. Chang , Qianjin Lu , Bruce C. Richardson

Book information

Publisher
Academic Press
Year
2015
ISBN
0128009578, 9780128009574
Language
english
Format
PDF
Filesize
12 MB (12325866 bytes)
Edition
1
Pages
520\496
Time added
2015-07-18 18:00:00

Description

Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs, sunlight, diet, stress, smoking, infection, etc.) in all stages of life (from a fetus in-utero to an elderly person) may result in epigenetic changes that lead to development of some skin diseases in life. They also discuss the possibilities of new and emergent epigenetic treatments which are gradually being adopted in management of various skin diseases. Chapters follow a conventional structure, covering fundamental biology of the disease condition, etiology and pathogenesis, diagnosis, commonly available treatments, and epigenetic therapy where applicable. • Discusses the basic biology of skin diseases and skin cancers induced or aggravated by aberrant epigenetic changes. • Evaluates how to approach autoimmune-related skin diseases from a therapeutic perspective using the wealth of emergent epigenetic clinical trials. • Offers a coherent and structured table of contents with basic epigenetic biology followed by discussion of the spectrum of rheumatologic through neoplastic skin diseases, finally ending with a discourse on epigenetic therapy.

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