ENGLISH

Kinomics: Approaches and Applications

By Heinz-Bernhard Kraatz , Sanela Martic

Book information

Publisher
Wiley-VCH
Year
2015
ISBN
3527337652, 9783527337651, 9783527683048, 3527683046, 9783527683055, 3527683054, 9783527683062, 3527683062, 9783527683031, 3527683038
Language
english
Format
PDF
Filesize
9 MB (9729937 bytes)
Edition
1
Pages
368\365
Time added
2015-09-02 20:09:13
Biochemistry Biological Sciences Science Math Biol

Description

Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown. The result is a toolbox for every kinase researcher: By addressing and comparing current approaches to the study of kinase action, both novice and established researchers will benefit from the practical knowledge contained in this invaluable reference.

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