ENGLISH

PET/CT in Cancer of Unknown Primary (Clinicians’ Guides to Radionuclide Hybrid Imaging)

By Nagabhushan Seshadri (editor) , Chinnamani Eswar (editor)

Book information

Publisher
Springer
Year
2017
ISBN
9783319564234, 9783319564241, 2017943813, 3319564234
Language
english
Format
PDF
Filesize
2 MB (2485539 bytes)
Edition
1st ed. 2017
Pages
80\76
Time added
2022-07-18 06:27:08

Description

This pocket book offers a rapid and concise overview of the utility of PET/CT in the management of patients with cancer of unknown primary (CUP). Readers will gain an appreciation of the unique information provided by PET/CT on the molecular and metabolic changes associated with CUP, which can occur in the absence of corresponding anatomical alterations. Characteristic imaging appearances are documented with the aid of a series of teaching cases that serve to illustrate the potential improvements in patient management that may be achieved through early use of PET/CT in the diagnostic pathway. In addition, the relation of the clinical and pathological background to imaging is explained. The book is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging (compiled under the auspices of the British Nuclear Medicine Society) and will be an excellent asset for all clinicians, nuclear medicine physicians, radiologists, radiographers, and nurses who routinely work in multidisciplinary teams involved in the management of these patients. Foreword Preface Acknowledgements Contents Contributors 1: Cancer of Unknown Primary (CUP) 1.1 Introduction 1.2 Epidemiology 1.3 Clinical Presentation/Signs and Symptoms 1.4 Diagnosis and Staging Procedures/Investigations 1.5 Prognosis References 2: An Overview of the Pathology of Cancer of Unknown Primary 2.1 Introduction 2.2 Immunohistochemistry 2.3 Molecular Diagnosis 2.4 Subsets References 3: An Overview of the Management of Cancer of Unknown Primary 3.1 Introduction 3.2 Surgical 3.3 Chemotherapy 3.4 Radiotherapy 3.5 Supportive Therapies 3.6 Management of CUP Patients Who Do Not Fall into Any Specific Subset References 4: Radiological Imaging in Cancer of Unknown Primary 4.1 Introduction 4.2 Ultrasound 4.3 Computed Tomography (CT) 4.4 MRI 4.5 Radionuclide Bone Scan 4.6 Limitations of Anatomical Imaging 4.7 Terminology 4.8 Multimodality Imaging and Multidisciplinary Team (MDT) Approach 4.9 Role of Imaging in Investigations and Management 4.10 Goals of a Standard CUP Workup 4.11 Biopsy and Histology: Important Considerations 4.12 Pearls and Pitfalls References 5: 18F-FDG and Non-FDG PET Radiopharmaceuticals 5.1 Introduction 5.2 PET Radiopharmaceuticals 5.2.1 18F-FDG 5.2.2 Non-FDG Radiopharmaceuticals References 6: Cancer of Unknown Primary: Role of FDG PET/CT 6.1 Introduction 6.2 Evidence for the Use of PET/CT in CUP 6.3 PET/CT in Response Assessment 6.4 PET/CT in Radiotherapy Planning 6.5 Stand-Alone PET Versus Combined PET/CT 6.6 PET/CT Protocols 6.7 Limitations 6.7.1 False Positives 6.7.2 False Negatives 6.8 Management Impact and Cost-Effectiveness 6.9 Future Directions 6.10 Recommendations References 7: Pictorial Atlas: Cancer of Unknown Primary 7.1 Case 1 7.1.1 Clinical Details 7.2 Case 2 7.2.1 Clinical Details 7.3 Case 3 7.3.1 Clinical Details 7.4 Case 4 7.4.1 Clinical Details 7.5 Case 5 7.5.1 Clinical Details 7.6 Case 6 7.6.1 Clinical Details 7.7 Case 7 7.7.1 Clinical Details 7.8 Case 8 7.8.1 Clinical Details 7.9 Case 9 7.9.1 Clinical Details 7.10 Case 10 7.10.1 Clinical Details 7.11 Case 11 7.11.1 Clinical Details 7.12 Case 12 7.12.1 Clinical Details 7.13 Case 13 7.13.1 Clinical Details 7.14 Case 14 7.14.1 Clinical Details 7.15 Case 15 7.15.1 Clinical Details Index

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