Diagnostic Electron Microscopy - A Practical Guide to Interpretation and Technique

Description

Diagnostic Electron Microscopy: A Practical Guide to Interpretation and Technique summarises the current interpretational applications of TEM in diagnostic pathology.  This concise and accessible volume provides a working guide to the main, or most useful, applications of the technique including practical topics of concern to laboratory scientists, brief guides to traditional tissue and microbiological preparation techniques, microwave processing, digital imaging and measurement uncertainty.The text features both a screening and interpretational guide for TEM diagnostic applications and current TEM diagnostic tissue preparation methods pertinent to all clinical electron microscope units worldwide. Containing high-quality representative images, this up-to-date text includes detailed information on the most important diagnostic applications of transmission electron microscopy as well as instructions for specific tissues and current basic preparative techniques. The book is relevant to trainee pathologists and practising pathologists who are expected to understand and evaluate/screen tissues by TEM. In addition, technical and scientific staff involved in tissue preparation and diagnostic tissue evaluation/screening by TEM will find this text useful.Content: Chapter 1 Renal Disease (pages 1–54): John W. Stirling and Alan CurryChapter 2 Transplant Renal Biopsies (pages 55–88): John BrealeyChapter 3 Electron Microscopy in Skeletal Muscle Pathology (pages 89–115): Elizabeth Curtis and Caroline SewryChapter 4 The Diagnostic Electron Microscopy of Nerve (pages 117–152): Rosalind KingChapter 5 The Diagnostic Electron Microscopy of Tumours (pages 153–180): Brian EydenChapter 6 Microbial Ultrastructure (pages 181–219): Alan CurryChapter 7 The Contemporary Use of Electron Microscopy in the Diagnosis of Ciliary Disorders and Sperm Centriolar Abnormalities (pages 221–236): P. Yiallouros, M. Nearchou, A. Hadjisavvas and K. KyriacouChapter 8 Electron Microscopy as a Useful Tool in the Diagnosis of Lysosomal Storage Diseases (pages 237–267): Joseph Alroy, Rolf Pfannl and Angelo A. UcciChapter 9 Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) (pages 269–275): John W. StirlingChapter 10 Diagnosis of Platelet Disorders by Electron Microscopy (pages 277–291): Hilary Christensen and Walter H. A. KahrChapter 11 Diagnosis of Congenital Dyserythropoietic Anaemia Types I and II by Transmission Electron Microscopy (pages 293–308): Yong?Xin RuChapter 12 Ehlers–Danlos Syndrome (pages 309–321): Trinh Hermanns?Le, Marie?Annick Reginster, Claudine Pierard?Franchimont and Gerald E. PierardChapter 13 Electron Microscopy in Occupational and Environmental Lung Disease (pages 323–340): Victor L. RoggliChapter 14 General Tissue Preparation Methods (pages 341–381): John W. StirlingChapter 15 Ultrastructural Pathology Today – Paradigm Change and the Impact of Microwave Technology and Telemicroscopy (pages 383–408): Josef A. SchroederChapter 16 Electron Microscopy Methods in Virology (pages 409–417): Alan CurryChapter 17 Digital Imaging for Diagnostic Transmission Electron Microscopy (pages 419–429): Gary Paul EdwardsChapter 18 Uncertainty of Measurement (pages 431–448): Pierre Filion