ENGLISH

The Combinatorial Index

Book information

Publisher
Academic Press
Year
1998
ISBN
9780080542409, 9780121413408, 0121413403
LCC
RS419.B86 1998
Open Library ID
OL713228M
Language
english
Format
PDF
Filesize
20 MB (21493140 bytes)
Edition
1
Pages
320\320
Library
mexmat
Time added
2009-11-09 02:42:13

Description

Combinatorial chemistry has become a major focus of research activity for pharmaceutical, agrochemical, and biotechnology companies. The explosion of combinatorial methods has created the need for a compendium of reliable synthetic transformations from the primary literature. The Combinatorial Index fills this need. Included are chapters on linkers, solid-phase synthetic methods, analytical techniques, and solution libraries. Procedures from the literature for constructing combinatorial libraries of small molecules comprise an indispensable laboratory reference for the synthetic chemist. Each procedure in the compilation is preceded by a section entitled "Points of Interest," which highlights the strengths and limitations of the various methods. A structural appendix covers both functional group transformations and heterocyclization reactions in solid-phase synthesis. This comprehensive but easy-to-access guide to the combinatorial chemistry literature will save time on tedious library searches, introduce a growing audience of chemists to this exciting field, and lower the barriers to attempting a new or related methodology.

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