Medicinal Chemistry and Drug Design

Description

Cover......Page 1 Medicinal Chemistry and Drug Design......Page 2 ©......Page 3 Contents......Page 5 Preface......Page 8 1 Kojic Acid Derivatives......Page 11 2 Analysis of Protein Interaction Networks to Prioritize Drug Targets of Neglected-Diseases Pathogens......Page 37 3 Recent Applications of Quantitative Structure-Activity r Relationships in Drug Design......Page 65 4 Atherosclerosis and Antihyperlipidemic Agents......Page 93 5 Inhibitors of Serine Proteinase - Application in Agriculture and Medicine......Page 113 6 Pyrrolobenzodiazepines as Sequence Selective DNA Binding Agents......Page 129 7 Regulation of EC-SOD in Hypoxic Adipocytes......Page 153 8 Development of an Ultrasensitive CRP Latex Agglutination Reagent by Using Amino Acid Spacers......Page 169 9 Pattern Recognition Receptors Based Immune Adjuvants: Their Role and Importance in Vaccine Design......Page 187 10 Microarray Analysis in Drug Discovery and Biomarker Identification......Page 213 11 Supraventricular Tachycardia Due to Dopamine Infused Through Epidural Catheter Accidentally (A Case Report and Review)......Page 237 12 Effective Kinetic Methods and Tools in Investigating the Mechanism of Action of Specific Hydrolases......Page 245 13 Aluminium - Non-Essential Activator of Pepsin: Kinetics and Thermodynamics......Page 285 14 Peptides and Peptidomimetics in Medicinal Chemistry......Page 307 15 Carbonic Anhydrase Inhibitors and Activators: Small Organic Molecules as Drugs and Prodrugs......Page 325 16 Stochastic Simulation for Biochemical Reaction Networks in Infectious Disease......Page 339 17 Alternative Perspectives of Enzyme Kinetic Modeling......Page 367 18 Molecular Modeling and Simulation of Membrane Transport Proteins......Page 383