ENGLISH

Natural Product Based Drug Discovery Against Human Parasites: Opportunities and Challenges

By Archana Singh (editor) , Brijesh Rathi (editor) , Anita K. Verma (editor) , Indrakant K. Singh (editor)

Book information

Publisher
Springer
Year
2023
ISBN
9811996040, 9789811996047
Language
english
Format
PDF
Filesize
13 MB (13236964 bytes)
Pages
615\602
Time added
2024-04-16 23:28:25

Description

This book comprehensively reviews current and novel treatment strategies against human parasites, including protozoans and helminths, using natural products. The initial chapters summarize the conventional treatment strategies and natural-product based therapeutics against these parasites. It discusses biochemical tools and techniques for the discovery of natural product based drugs against human parasites. The book also covers the ingenious and innovative mechanisms to achieve drug resistance by the protozoan parasites and strategies to overcome the resistance. It entails mechanistic insight into the modulation of host immune responses to delay or inhibit parasite clearance and explores host-pathogen interactions that mediate immunity against subsequent parasite challenge. In turn, the volume helps in understanding the immunobiology of the parasites and tools to identify candidate vaccine antigens and novel delivery systems against the protozoan parasites. Lastly, it explores the role of advanced methods, including nanotechnology, marine bioprospecting, and microorganisms-derived biochemicals against the protozoan parasites. This book is useful for students and researchers of pharmacology, parasitology, zoology and other allied fields.​

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