ENGLISH

Microtubule Protocols

By Jun Zhou (eds.) , Richard H. Wade PhD (auth.)

Book information

Publisher
Humana Press
Year
2007
ISBN
1597454427, 9781597454421, 9781588296429, 1588296423
DOI
10.1007/978-1-59745-442-1
Open Library ID
OL12325671M
Language
english
Format
PDF
Filesize
4 MB (4288961 bytes)
Series
Methods in Molecular Medicine 137
Edition
1
Pages
305\307
Topic
Medicine
Orientation
no
Scanned
no
Time added
2010-05-17 00:23:50
Cell Biology; Medicinal Chemistry; Cancer Research

Description

Microtubules are essential components of the cytoskeleton, and play critical roles in a variety of cell processes, including cell shaping, intracellular tracking, cell division, and cell migration. Microtubule Protocols presents a comprehensive collection of essential and up-to-date methods for studying both the biology of microtubules and the mechanisms of action of microtubule-interacting drugs. The straightforward presentation of readily reproducible protocols is a hallmark of the Methods in Molecular Medicine™ series, and is evident in this volume. Methods presented range from the purification and characterization of microtubule proteins, analysis of post-translational modifications of tubulin, and determination of microtubule structure, to the visualization of microtubule and spindle behavior, measurement of microtubule dynamics, and examination of microtubule-mediated cellular processes. Both basic scientists and clinical researchers will benefit from this collection of state-of-the-art protocols for microtubule research.

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