ENGLISH

Bacterial Toxins: Tools in Cell Biology and Pharmacology

By Klaus Aktories

Book information

Publisher
Wiley-VCH
Year
2002
ISBN
3527308814, 9783527308811
Open Library ID
OL9326871M
Language
english
Format
PDF
Filesize
25 MB (25797833 bytes)
Series
Laboratory Companion
Pages
323\323
Library
duansci.com
Time added
2010-05-17 00:23:50

Description

This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed descriptions of the methodology include the engineering and use of modified and chimeric toxins for better performance. A solid introduction to toxin structure and functions, as well as a valuable source of methodology for researchers in molecular biology, pharmacology and experimental medicine.

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